Manifestaciones urológicas de la enfermedad relacionada a IgG4
DOI:
https://doi.org/10.48193/revistamexicanadeurologa.v80i5.610Palabras clave:
Pseudotumor, IgG4, Urologia, AutoinmuneResumen
La enfermedad relacionada con IgG4 (ER-IgG4) es una entidad clínica caracterizada por una concentración sérica elevada e inflamación similar a un tumor con infiltración de tejido por IgG4 y células plasmáticas. Aunque la ER-IgG4 es rara pero clínicamente significativa, sus manifestaciones urológicas se han reportado en la literatura. Esta revisión ofrece un panorama completo que explica las patologías relacionadas en el área urológica.
Desde que Terumi Kamisawa reconoció por primera vez la ER-IgG4 en el año 2003, caracterizada por lesiones multiorgánicas en pacientes con pancreatitis autoinmune, clasificada como una entidad inflamatoria y fibrótica con tumores e infiltración linfoplasmocítica densa, positiva a IgG4.(1–3) Presentada en población de mediana edad, entre 59-68 años, sin una distribución clara del sexo, (4–6) se presenta con diversas manifestaciones clínicas y como manifestación urológica principal tumores pseudoinflamatorios y sintomatología de tracto urinario bajo. Esta revisión ofrece una visión general y clara de la enfermedad desde la fisiopatología, el diagnóstico y el tratamiento desde un punto de vista urológico.
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