Manifestaciones urológicas de la enfermedad relacionada a IgG4

  • Benjamin Enrique Montaño Roca Instituto de Seguridad Social del Estado de México y Municipios. Centro Médico Arturo Montiel Rojas, Toluca, México. https://orcid.org/0000-0001-8750-0320
  • Davide Vanacore Aix-Marseille Université, Marsella, Francia https://orcid.org/0000-0001-5229-7385
  • Gustavo Gallegos Sánchez Instituto de Seguridad Social del Estado de México y Municipios. Centro Médico Arturo Montiel Rojas, Toluca, México. https://orcid.org/0000-0003-4671-241X
  • César Eduardo Rosales Velázquez Instituto de Seguridad Social del Estado de México y Municipios. Centro Médico Arturo Montiel Rojas, Toluca, México. https://orcid.org/0000-0003-1853-1064
  • Guillermo Enrique Ruvalcaba Oceguera Instituto de Seguridad Social del Estado de México y Municipios. Centro Médico Arturo Montiel Rojas, Toluca, México. https://orcid.org/0000-0003-4673-976X
  • Marco Antonio Aragón Castro Instituto de Seguridad Social del Estado de México y Municipios. Centro Médico Arturo Montiel Rojas, Toluca, México. https://orcid.org/0000-0002-6433-6094
  • Rubén Gutiérrez Rosales Instituto de Seguridad Social del Estado de México y Municipios. Centro Médico Arturo Montiel Rojas, Toluca, México. https://orcid.org/0000-0003-2522-6287
  • Romain Boissier Aix-Marseille Université, Marsella, Francia https://orcid.org/0000-0001-6428-0273
Palabras clave: Pseudotumor, IgG4, Urologia, Autoinmune

Resumen

La enfermedad relacionada con IgG4 (ER-IgG4) es una entidad clínica caracterizada por una concentración sérica elevada e inflamación similar a un tumor con infiltración de tejido por IgG4 y células plasmáticas. Aunque la ER-IgG4 es rara pero clínicamente significativa, sus manifestaciones urológicas se han reportado en la literatura. Esta revisión ofrece un panorama completo que explica las patologías relacionadas en el área urológica.

Desde que Terumi Kamisawa reconoció por primera vez la ER-IgG4 en el año 2003, caracterizada por lesiones multiorgánicas en pacientes con pancreatitis autoinmune, clasificada como una entidad inflamatoria y fibrótica con tumores e infiltración linfoplasmocítica densa, positiva a IgG4.(1–3) Presentada en población de mediana edad, entre 59-68 años, sin una distribución clara del sexo, (4–6) se presenta con diversas manifestaciones clínicas y como manifestación urológica principal tumores pseudoinflamatorios y sintomatología de tracto urinario bajo. Esta revisión ofrece una visión general y clara de la enfermedad desde la fisiopatología, el diagnóstico y el tratamiento desde un punto de vista urológico.

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Publicado
2020-10-28
Sección
Artículos de revisión