Correlación de la severidad de los síntomas del tracto urinario inferior en hombres con diabetes mellitus.
DOI:
https://doi.org/10.48193/nxamkx38Palabras clave:
Síntomas del tracto urinario inferior, Diabetes mellitus, Correlación de datosResumen
Objetivo: Determinar la correlación de la severidad de los STUI en hombres con diabetes mellitus; Material y Métodos: Estudio transversal y analítico en una unidad de medicina familiar en la CDMX durante el 2022 en 338 sujetos, se evaluó la severidad de los STUI mediante la Escala Visual Análoga Gea®, el análisis fue por estadística descriptiva e inferencial mediante correlación Rho de Spearman, tomando p <0.05 para la significancia estadística. Resultados: Se encontró diferencia entre la severidad de nicturia con DM, con mayor frecuencia de nicturia en la DM; encontrando correlaciones bajas en algunos síntomas de STUI con edad, tabaquismo e HPB; calidad de vida con correlaciones negativas bajas a moderadas con todos los STUI. Limitaciones del estudio: Similar a investigaciones previas, carencia de temporalidad. Originalidad: Pocas investigaciones demuestran que los STUI no están directamente relacionados con la DM. Conclusiones: Las correlaciones entre diabetes y síntomas del tracto urinario inferior fueron pobres y en su mayoría no significativas, a pesar que hay literatura mencionando esta asociación, no es suficiente para deducir que la diabetes corresponda a un factor determinante en la severidad de los STUI. Palabras clave: Síntomas del tracto urinario inferior, Diabetes Mellitus, Correlación de datos.
Referencias
Saigal, CS, Joyce G. Economic costs of benign prostatic hyperplasia in the private sector. J Urol. 2005 Apr;173(4):1309-13. DOI: https://doi.org/10.1097/01.ju.0000152318.79184.6f
Abler LL, Vezina CM. Links between lower urinary tract symptoms, intermittent hypoxia and diabetes: Causes or cures?. Respir Physiol Neurobiol. 2018 Oct;256:87-96. DOI: https://doi.org/10.1016/j.resp.2017.09.009
Choi EPH, Wan EYF, Chin WY, Lam CLK. Lower urinary tract symptoms and health-related quality of life in Hong Kong primary care: a cross-sectional study. Qual Life Res. 2020 May;29(5):1311-1321. DOI: https://doi.org/10.1007/s11136-019-02402-7
Robertson C, Link CL, Onel E, Mazzetta C, Keech M, Hobbs R, et al. The impact of lower urinary tract symptoms and comorbidities on quality of life: the BACH and UREPIK studies. 2007 Feb;99(2):347-54. DOI: https://doi.org/10.1111/j.1464-410x.2007.06609.x
Boyle P, Robertson C, Mazzetta C, Keech M, Hobbs R, Fourcade R, et al. The relationship between lower urinary tract symptoms and health status: the UREPIK study. BJU Int. 2003 Dec;92(9):943-7. DOI: https://doi.org/10.1046/j.1464-410x.2003.04448.x
Przydacz M, Skalski M, Sobanski J, Chlosta M, Raczynski K, Klasa K, et al. Association between Lower Urinary Tract Symptoms and Sleep Quality of Patients with Depression. Medicina (Kaunas). 19 Apr 2021, 57(4):394. DOI: https://doi.org/10.3390/medicina57040394
Perchon LF, Pintarelli VL, Bezerra E, Thiel M, Dambros M. Quality of life in elderly men with aging symptoms and lower urinary tract symptoms (LUTS). Neurourol Urodyn. 2011 Apr;30(4):515-9. DOI: https://doi.org/10.1002/nau.21008
Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. 2018 Feb;14(2):88-98. DOI: https://doi.org/10.1038/nrendo.2017.151
Boon TA, Van Venrooij GE, Eckhardt MD. Effect of diabetes mellitus on lower urinary tract symptoms and dysfunction in patients with benign prostatic hyperplasia. Curr Urol Rep. 2001 Aug;2(4):297-301. DOI: https://doi.org/10.1007/s11934-001-0067-z
Madersbacher S, Sampson N, Culig Z. Pathophysiology of Benign Prostatic Hyperplasia and Benign Prostatic Enlargement: A Mini-Review. Gerontology. 2019;65(5):458-464. DOI: https://doi.org/10.1159/000496289
Sebastianelli A, Gacci M. Current Status of the Relationship Between Metabolic Syndrome and Lower Urinary Tract Symptoms. Eur Urol Focus. 2018 Jan;4(1):25-27. DOI: https://doi.org/10.1016/j.euf.2018.03.007
Tam CA, Helfand BT, Erickson BA. The Relationship Between Diabetes, Diabetes Severity, Diabetes Biomarkers, and the Presence of Lower Urinary Tract Symptoms: Findings From the National Health and Nutrition Examination Survey. Urology. 2017 Jul;105:141-148. DOI: https://doi.org/10.1016/j.urology.2017.03.040
Vinik AI, Maser RE, Mitchell BD, Freeman R. Diabetic autonomic neuropathy. Diabetes Care. 2003 May;26(5):1553-79. DOI: https://doi.org/10.2337/diacare.26.5.1553
Sarma AV, St Sauver JL, Hollingsworth JM, Jacobson DJ, McGree ME, Dunn RL, et al. Urologic Diseases in America Project. Diabetes treatment and progression of benign prostatic hyperplasia in community-dwelling black and white men. Urology. 2012 Jan;79(1):102-8. DOI: https://doi.org/10.1016/j.urology.2011.08.065
Menéndez V, Cofán F, Talbot-Wright R, Ricart MJ, Gutiérrez R, Carretero P. Urodynamic evaluation in simultaneous insulin-dependent diabetes mellitus and end stage renal disease. 1996 Jun;155(6):2001-4.
Johnson TV, Abbasi A, Ehrlich SS, Kleris RS, Schoenberg ED, Owen-Smith A, et al. Patient misunderstanding of the individual questions of the American Urological Association symptom score. J Urol. 2008 Jun;179(6):2291-4. DOI: https://doi.org/10.1016/j.juro.2008.01.140
Barry MJ, Fowler FJ Jr, O’Leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK, et al. The American Urological Association symptom index for benign prostatic hyperplasia. 1992 Nov;148(5):1549-57. DOI: https://doi.org/10.1016/s0022-5347(17)36966-5
Johnson TV, Schoenberg ED, Abbasi A, Ehrlich SS, Kleris R, Owen-Smith A, et al. Assessment of the performance of the American Urological Association symptom score in 2 distinct patient populations. J Urol. 2009 Jan;181(1):230-7. DOI: https://doi.org/10.1016/j.juro.2008.09.010
Preciado-Estrella DA, Kaplan SA, Iturriaga-Goyón E, Ramón-Trejo E, Mayorga-Gómez E, Auza-Benavides A, et al. Comparación del Índice Internacional de Síntomas Prostáticos versus Escala Visual Análoga Gea® para la evaluación de los síntomas de la vía urinaria inferior. Rev Mex Urol. 2017 sep-oct;77(5):372-382.
Daneshgari F, Liu G, Hanna-Mitchell A. Path of translational Discovery of urológical complications of obesity and diabetes. Am J Physiol Renal Physiol. 2017 May 1;312(5):F887-F896. DOI: https://doi.org/10.1152/ajprenal.00489.2016
Mahle HM, Popovicz D, Paes R, Assis GM, Coradassi T, Erzinger AR. Association between diabeic neuropathy and lower urinary tracts symptoms in people with diabtes mellitus: integrative review. Eectronic Journal Collection Health (2020); 12(12), 1-11.
Qasrawi H, Tabouni M, Almansour SW, Ghannam M, Abdalhaq A, Abushamma F, et al. An evaluation of lower urinary tract symptoms in diabetic patients: a cross-sectional study. BMC Urol. 2022 Nov 10;22(1):178. DOI: https://doi.org/10.1186/s12894-022-01133-1
Erdogan BR, Liu G, Arioglu-Inan E, Michel MC. Established and emerging treatments for diabetes associated lower tract dysfuncion. Naunyn-Schmiederberg’s Archives of Pharmacology (2022); 395(8), 887-906. DOI: https://doi.org/10.1007/s00210-022-02249-9
Tai HC, Tai TY, Yang WS, Wang SW, Yu HJ. Associations between lower urinary tract dysfunction and glycemic control in women with type 2 diabetes: A cross sectional study. J Diabetes Complications. 2016 Apr;30(3):415-9. DOI: https://doi.org/10.1016/j.jdiacomp.2016.01.002
Yoshimura K. Correlates for nicturia: A review of epidemiological studies. Int J Urol. 2012 Apr;19(4):317-29. DOI: https://doi.org/10.1111/j.1442-2042.2011.02956.x
Welliver C, Sulaver R, Whittington A, Helfand BT, Cakir ÖO, Griffith JW, et al. Analyzing why men seek treatment for lower urynary tract symptoms and facto associated with nonimprovement. Urology. 2015 Nov;86(5):862-7. DOI: https://doi.org/10.1016/j.urology.2015.08.006
Conchado J, Álvarez R, Serrano C. Benign prostatic hyperplasia and lower tract urinary tract symptoms. Revi Cubana Med Gen Itegr 2021; 37(1): 1-14.
Maserejian NN, Chen S, Chiu GR, Araujo AB, Kupelian V, Hall SA, et al. Treatment status and progression or regression of lower urinary tract symptoms in a general adult population sample. The Journal Of Urology. 2014 January;191(1); 107-113. DOI: https://doi.org/10.1016/j.juro.2013.07.005
Montero A, Bermúdez F, Feito D. Relationship betweeen lower urinary tract symptoms in men and erectile dysfunction. Semergen. 2016 Apr;42(3):164-71. DOI: https://doi.org/10.1016/j.semerg.2015.07.005
Noegroho B, Siregar S, Simangunson A. Correlation of viceral obesity and interleukin-6 level on luts due to benign prostatic. Res Rep Urol. 2021 Jun 16;13:369-373. DOI: https://doi.org/10.2147%2FRRU.S310269
Bauer SR, Harrison SL, Cawthon PM, Senders A, Kenfield SA, Sukind AM et al. Longitudinal changes in adiposity lower urinary tract symptoms among older men. J Gerontol A Biol Sci Med Sci. 2022 Oct 6;77(10):2102-2109. DOI: https://doi.org/10.1093/gerona/glab227
Furukawa S, Sakai T, Niiya T, Miyaoka H, Miyake T, Yamamoto S, et al. Obesity and the prevalence of nocturia in japanese elderly patients wth tipe 2 diabetes mellitus: The dogo study. Geriatrics and Gerontology 2017; 17(12), 2460-2465. DOI: https://doi.org/10.1111/ggi.13103
Johnson TM, Sattin RW, Parmelee P, Fultz NH, Ouslander JG. Evaluating potentially modificable risk factors for prevalent and incident nocturia in older adults. J Am Geriatr Soc. 2005 Jun;53(6):1011-6. DOI: https://doi.org/10.1111/j.1532-5415.2005.53321.x
Lombardo R, Tubaro A, Burkhard F. Nocturia: The Complex Role of the Heart, Kidneys, and Bladder. Eur Urol Focus. 2020 May 15;6(3):534-536. DOI: https://doi.org/10.1016/j.euf.2019.07.007
Ohishi M, Kubozono T, Higuchi K, Akasaki Y. Hypertension, cardiovascular disease, and noctirua: a systematic review of the pathophysiological mechanisms. Hypertension Research (2021); 44(7), 733-739. DOI: https://doi.org/10.1038/s41440-021-00634-0
Feldstein CA. Nocturia in arterial hypertension: a prevalent, underreported, and sometimes underestimated association. J Am Soc Hypertens. 2013 Jan-Feb;7(1):75-84. DOI: https://doi.org/10.1016/j.jash.2012.12.004
Chen FY, Dai YT, Liu CK, Yu HJ, Liu CY, Chen T. Perception of nocturia and medical consulting behaivor among community-dwelling women. International Urogymecology Journal 2007 July;18: 431-436. DOI: https://doi.org/10.1007/s00192-006-0167-x
Jura YH, Townsend MK, Curhan GC, Resnick NM, Grodstein F. Caffeine and risk of stress, urgency, and mixed urinary incontinence. National Institute of Heath 2011 May;188(5): 1775-1780. DOI: https://doi.org/10.1016/j.juro.2011.01.003
Bird ET, Parker BD, Kim HS, Coffield KS. Caffeine lingestion and lower urinary tract symptoms in healthy volunteers. Neurourol Urodyn. 2005;24(7):611-5. DOI: https://doi.org/10.1002/nau.20179
Staack A, Dilstelberg B, Schlaifer A, Sabaté J. Prospective study on the effects of regular and decaffeinated coffe on urinary symptoms in Young and healthy volunteers. Neurourol Urodyn. 2017 Feb;36(2):432-437. DOI: https://doi.org/10.1002/nau.22949
Kennedy O, Pirastu N, Poole R, Fallowfield J, Hayes PC, Grzeszkowiak, et al. Coffee Consumption and Kidney Function: A Mendelian Randomization Study. Am J Kidney Dis. 2020 May;75(5):753-761. DOI: https://doi.org/10.1053/j.ajkd.2019.08.025
Brigham K. The Epidemiology of Benign Prostatic Hyperplasia Associated with Lower Urinary Tract Symptoms: Prevalence and Incident Rates. Urol Clin North Am. 2016 Aug;43(3):289-97. DOI: https://doi.org/10.1016/j.ucl.2016.04.001
Carvajal G. Relación entre el antígeno prostático especifico y la hiperplasia prostática benigna en pacientes mexicanos. Estudio REPSA. Revista Mexicana de Urología 2014 November-December;74(6),342-345. DOI: https://doi.org/10.48193/revistamexicanadeurologa.v74i6.214
Hang EP, Fai EY, Yee W, Kuen C. Lower urinary tract symptoms and health-related quality of life in Hong Kong primary care: a cross-sectional study. Qual Life Res. 2020 May;29(5):1311-1321. DOI: https://doi.org/10.1007/s11136-019-02402-7
