Bladder granular cell tumor: report of a rare finding and literature review
DOI:
https://doi.org/10.48193/revistamexicanadeurologa.v83i1.835Keywords:
Granular cell tumor, bladder, neoplasmsAbstract
Case description: A 68-year-old man with a constitutional syndrome secondary to an abscess in the psoas, which was incidentally diagnosed in the CT scan of a possible neoplastic lesion. Cystoscopy identifies a polypoid neoformation that is completely removed by transurethral resection, being diagnosed as a granular cell tumor of the bladder.
Relevance: The granular cell tumor is a rare neoplasm, in bladder there are only 27 cases published. These lesions are mostly benign, although cases of a malignant nature have been described. Due to their asymptomatic presentation, there is an underdiagnosis of these lesions, which translates into a lack of clinical and therapeutic information, without the existence of guidelines for their management.
Clinical implications: It is important to know the clinical and histological characteristics of this pathology because its symptoms mimic some neoplasms of the bladder. It is also important to know the entity to perform a correct treatment, considering its characteristic recurrence tendency.
Conclusion: Despite being infrequent lesions, due to the recurrence tendency and their possible malignant nature, it is important to consider them as a possible differential diagnosis in bladder lesions.
References
Abrikossoff A. Über Myome. Virchows Archiv für pathologische Anatomie und Physiologie und für klinische Medizin. 1926;260(1): 215–233. https://doi.org/10.1007/BF02078314.
Humphrey PA, Moch H, Cubilla AL, Ulbright TM, Reuter VE. The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part B: Prostate and Bladder Tumours. European Urology. 2016;70(1): 106–119. https://doi.org/10.1016/j.eururo.2016.02.028.
Sun Y, Reuter VE, Magi-Galluzzi C, Sankin A, Epstein JI. Granular Cell Tumor of the Bladder: A Report of Six Cases. Urology. 2018;121: 203.e1-203.e5. https://doi.org/10.1016/j.urology.2018.08.018.
Ravich A, Stout AP, Ravich RA. Malignant Granular Cell Myoblastoma Involving the Urinary Bladder. Annals of Surgery. 1945;121(3): 361–372. https://doi.org/10.1097/00000658-194503000-00010.
Abbas F, Memon A, Siddiqui T, Kayani N, Ahmad NA. Granular cell tumors of the urinary bladder. World Journal of Surgical Oncology. 2007;5: 33. https://doi.org/10.1186/1477-7819-5-33.
Marcoval J, Bauer-Alonso A, Llobera-Ris C, Moreno-Vilchez C, Penín RM, Bermejo J. Tumor de células granulares. Estudio clínico de 81 pacientes. Actas Dermo-Sifiliográficas. 2021;112(5): 441–446. https://doi.org/10.1016/j.ad.2020.11.012.
Knief J, Becker JU, Kreipe HH, Kuczyk MA, Gabuev A, von Klot C. Granular cell tumour of the urinary bladder. Rare Tumors. 2012;4(2): e22. https://doi.org/10.4081/rt.2012.e22.
Tufano A, Canale V, Di Lascio G, Coppola G, Flammia RS, Cristini C. Atypical granular cell tumor of the urinary bladder: A case report and literature review. Urology Case Reports. 2021;38: 101669. https://doi.org/10.1016/j.eucr.2021.101669.
Kang HW, Kim YW, Ha YS, Min YK, Kim WT, Kim YJ, et al. Granular cell tumor of the urinary bladder. Korean Journal of Urology. 2010;51(4): 291–293. https://doi.org/10.4111/kju.2010.51.4.291.
Yarlagadda VK, Benson DG, Gordetsky JB, Rais-Bahrami S. Granular Cell Tumor of the Bladder: A Rare Neoplasm Managed With Robotic Partial Cystectomy Using Near-infrared Filter Guidance. Urology. 2017;103: 7–11. https://doi.org/10.1016/j.urology.2016.11.024.
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