Bellini’s collecting duct renal carcinoma: report of two cases and review of the literature

Authors

  • Garazi Gutiérrez-Zurimendi Hospital Universitario Cruces, Barakaldo, Bizkaia. España
  • Gonzalo García de Casasola-Rodríguez Hospital Universitario Cruces, Barakaldo, Bizkaia. España
  • Ibon Urrestizala-Peña Hospital Universitario Galdakao, Galdakao, Bizkaia. España
  • Mikel Aizcorbe-Gómez Hospital Universitario Cruces, Barakaldo, Bizkaia. España
  • Asier Maldonado-De Sasia Hospital Universitario Cruces, Barakaldo, Bizkaia. España
  • Aranzazu Urresola-Olabarrieta Hospital Universitario Cruces, Barakaldo, Bizkaia. España

DOI:

https://doi.org/10.48193/revistamexicanadeurologa.v82i1.730

Keywords:

Bellini’s collecting duct renal carcinoma, renal cancer, urothelial cancer, nephrectomy, chemotherapy

Abstract

Abstract

Clinical cases: We present two cases of Bellini’s Collecting Duct Renal Carcinoma (CDRC) that appear as suspicious kidney masses with enhancement of the urotelium, without a determinant radiological appearance, diagnosed by anatomo-pathological analysis. We revise the medical history, histological findings and make a review of the literature.

Importance / Clinical implication: Bellini’s collecting duct renal carcinoma is a very rare and aggressive type of kidney cancer (less than 1%), usually diagnosed at advanced stages. It does not present specific radiological characteristics, which makes necessary the histologic and inmunohistochemical analysis to confirm the diagnosis. We must suspect CDRC in infiltrative medular renal masses that do not affect kidney shape, and treat as soon as possible performing surgery, whenever feasible, normally associated with adjuvant chemotherapy. Nevertheless, it usually has an unfavourable evolution.

Conclusion: It is imperative to diagnose and treat this kind of tumours as soon as possible due to its aggressiveness and fatal prognosis.

 

References

American Cancer Society. Key Statistics About Kidney Cancer. Cancer. 2022. [accessed 1 Feb 2022] Available from: https://www.cancer.org/cancer/kidney-cancer/about/key-statistics.html

Gutiérrez-Domingo A, Gutiérrez-Domingo I, Gallardo-Rodríguez K, Rodríguez-Caulo A. Carcinoma de los conductos colectores de Bellini: una alteración poco frecuente y de mal pronóstico. Rev Mex Urol. 2017 May 26;77(3). [accessed 1 Feb 2022] Available from: https://revistamexicanadeurologia.org.mx/index.php/rmu/article/view/34

García-Fadrique G, Ramírez-Backhaus M, Morales G, Pontones JL, Jiménez-Cruz JF. Carcinoma de los conductos colectores de bellini. Presentación de un caso y revisión de la literatura. Actas Urol Esp. 2010 Jul;34(7):639–41. doi: http://dx.doi.org/10.1016/j.acuro.2010.01.024

Craver RD, Correa H, Crapanzano JP, Kumar SR, Gardner RV. Renal collecting duct carcinoma in an 8-year-old child. Pediatr Nephrol Berl Ger. 1996 Feb;10(1):29–32. doi: https://doi.org/10.1007/bf00863434

Mishra AK, Manikandan R, Dorairajan LN, Mittal JK, Rekha JS. Bellini Duct Carcinoma: A Rare Entity. J Clin Diagn Res JCDR. 2016 Oct;10(10):PD01–2. doi: https://dx.doi.org/10.7860%2FJCDR%2F2016%2F21335.8613

Vecchione A, Galetti TP, Gardiman M, Ishii H, Giarnieri E, Pagano F, et al. Collecting duct carcinoma of the kidney: an immunohistochemical study of 11 cases. BMC Urol. 2004 Sep 9;4(1):11. doi: https://doi.org/10.1186/1471-2490-4-11

Husillos A, Herranz-Amo F, Subirá D, Lledó E, Molina-Escudero R, Hernández-Fernández C. [Collecting duct renal cell carcinoma]. Actas Urol Esp. 2011 Jun;35(6):368–71. doi: https://doi.org/10.1016/j.acuro.2011.01.012

Hu YU, Zhou H, Wang G, Song Z, Zhao C, Wang Y. Collecting duct carcinoma of the kidney: A case report. Oncol Lett. 2015 Jun;9(6):2902–4. doi: https://doi.org/10.3892/ol.2015.3085

Méjean A, Rouprêt M, Larousserie F, Hopirtean V, Thiounn N, Dufour B. Is there a place for radical nephrectomy in the presence of metastatic collecting duct (Bellini) carcinoma? J Urol. 2003 Apr;169(4):1287–90. doi: https://doi.org/10.1097/01.ju.0000050221.51509.f5

Díaz Pérez JA, Zamora CJ, García Vera JA, Melo Uribe MA, García Ayala E. [Bellini collecting duct renal carcinoma: case report]. Arch Esp Urol. 2008 Feb;61(1):67–71. doi: https://doi.org/10.4321/s0004-06142008000100010

Corbetta J, Sívori F, Ale R, Verdinelli J, González O, Besuchio S, et al. Carcinoma de los túbulos colectores de Bellini. Rev Argent Urol. 2001;66(4):173–82.

San Miguel Fraile P, Dos Santos JE, Delgado C, Zungri Telo E, Alvarez C, Iglesias B. [Low grade collecting duct carcinoma of the kidney. Presentation of one case and literature revision]. Actas Urol Esp. 2004 Jun;28(6):478–83. doi: https://doi.org/10.1016/s0210-4806(04)73115-0

Uruñuela FL, Calvo JJ, Garibay AMSG de, Aristu JIJ, Paul MAP, Troyas RG, et al. Carcinoma de ductos colectores de Bellini. Arch Esp Urol. 2004;57(2):153–6.

Ozcan A, Krishnan B, Truong L. Renal Tumors. In: McManus LM, Mitchell RN, editors. Pathobiology of Human Disease. San Diego: Academic Press; 2014. p. 2869–99. [accessed 1 Feb 2022] Available from: https://doi.org/10.1016/B978-0-12-386456-7.05415-0

Qian X, Wang Z, Zhang J, Wang Q, Zhou P, Wang S, et al. Clinical Features and Prognostic Outcome of Renal Collecting Duct Carcinoma: 12 Cases from a Single Institution. Cancer Manag Res. 2020;12:3589–95. doi: https://doi.org/10.2147/CMAR.S244094

Downloads

Published

2022-02-21 — Updated on 2022-02-22

Versions

Issue

Vol. 82 No. 1 (2022): January-February

Section

Clinical cases