Penile paraffinoma secondary to mineral oil injections
DOI:
https://doi.org/10.48193/revistamexicanadeurologa.v80i6.688Keywords:
Diseases of the penis, foreign body reaction, penile induration, injection site reaction, mineral oilAbstract
Clinical case description: A 71-year-old man that received injections of mineral oil and a multivitamin complex in the subcutaneous tissue and corpora cavernosa of the penis, for 8 months, presented with penile deformity and progressive edema of the dorsal region. He came to our hospital 4 days after the lesion had been excised, presenting with necrosis of the penile skin and purulent drainage, requiring resection and debridement of the necrotic tissue.
Relevance: The unauthorized injection of substances into the penis for cosmetic or sexual purposes has been on the rise in recent years.
Clinical implications: Penile paraffinoma is a reaction caused by the injection of foreign substances into the penis. Said injections often produce complications that can appear months or years after application and they can be life-threatening.
Conclusions: The injection of foreign substances into the subcutaneous tissue of the penis can produce severe and devastating complications. Opportune treatment and multidisciplinary management are key to satisfactory patient progression.
References
Svensøy JN, Travers V, Osther PJS. Complications of penile self-injections: investigation of 680 patients with complications following penile self-injections with mineral oil. World J Urol. 2018 Jan;36(1):135–43. doi: https://doi.org/10.1007/s00345-017-2110-9
de Almeida Issa MC, Alexandre DC, Almeida RD, Durães SMB. Penile paraffinoma necrosis after mineral oil injection applied by a non-medical pro-fessional.
Bjurlin MA, Carlsen J, Grevious M, Jordan MD, Taylor A, Divakaruni N, et al. Mineral Oil-induced Sclerosing Lipogranuloma of the Penis. J Clin Aesthet Dermatol. 2010 Sep;3(9):41–4.
Oh KJ, Park K, Kang TW, Kwon DD, Ryu SB. Subcutaneous metallic mercury injection for penile augmentation. Urology. 2007 Jan;69(1):185.e3-4. doi: https://doi.org/10.1016/j.urology.2006.10.028
Glicenstein J. [The first ‘fillers’, vaseline and paraffin. From miracle to disaster]. Ann Chir Plast Esthet. 2007 Apr;52(2):157–61. doi: https://doi.org/10.1016/j.anplas.2006.05.003
Hohaus K, Bley B, Köstler E, Schönlebe J, Wollina U. Mineral oil granuloma of the penis. J Eur Acad Dermatol Venereol. 2003 Sep;17(5):585–7. doi: https://doi.org/10.1046/j.1468-3083.2003.00896.x
Al-Ansari AA, Shamsodini A, Talib RA, Gul T, Shokeir AA. Subcutaneous cod liver oil injection for penile augmentation: review of literature and report of eight cases. Urology. 2010 May;75(5):1181–4. doi: https://doi.org/10.1016/j.urology.2009.11.023
Pehlivanov G, Kavaklieva S, Kazandjieva J, Kapnilov D, Tsankov N. Foreign-body granuloma of the penis in sexually active individuals (penile paraffinoma). J Eur Acad Dermatol Venereol. 2008 Jul;22(7):845–51. doi: https://doi.org/10.1111/j.1468-3083.2008.02677.x
Redmond E, Forde JC, Flood HD. Filling the void: a case of sepsis following the injection of a penile bulking agent. BMJ Case Rep. 2014 Mar 26;2014. doi: https://doi.org/10.1136/bcr-2013-203054
Shamsodini A, Al-Ansari AA, Talib RA, Alkhafaji HM, Shokeir AA, Toth C. Complications of penile augmentation by use of nonmedical industrial silicone. J Sex Med. 2012 Dec;9(12):3279–83. doi: https://doi.org/10.1111/j.1743-6109.2011.02563.x
Zurimendi GG, Albisu-Tristán A, Gil-Martín AR, Casasola-Rodríguez GG de, Lozano-Ortega JL, Urresola-Olabarrieta A, et al. Inflamación granulomatosa peneana por inyección de sustancia extraña. Revista Mexicana de Urología. 2019 Apr 5;79(1):1–6.