Eosinophilic cystitis in pediatric age. Case review
DOI:
https://doi.org/10.48193/revistamexicanadeurologa.v83i5.1052Keywords:
Eosinophilic cystitis, pediatric, inflammation, bladderAbstract
Eosinophilic cystitis (EC) is a rare disease that is characterized by inflammation of the bladder wall and whose etiology is still not well known. Less than 30 cases have been reported in the pediatric age. The symptoms, laboratory tests, and imaging studies are usually nonspecific, so the definitive diagnosis is by histopathology. Treatment, in most cases, is conservative (antihistamines, anti-inflammatories).
We present two cases of patients diagnosed with eosinophilic cystitis which appeared to be a bladder tumor in the initial evaluation. The diagnosis was confirmed by histopathological study after taking a sample of the tissue during cystoscopy. Both patients maintained conservative treatment remitting all their symptoms. Two years later patients remain asymptomatic.
As there are few reports in literature these clinical cases are presented to share our experience regarding clinical manifestations, diagnosis, and management of eosinophilic cystitis.
References
Abilov A, Özcan R, Polat E, Dervişoğlu S, Emir H. Rare cause of dysuria: Eosinophilic cystitis. Journal of Pediatric Urology. 2013;9(1):e6–8. doi: https://doi.org/10.1016/j.jpurol.2012.04.005
Pomeranz A, Eliakim A, Uziel Y, Gottesman G, Rathaus V, Zehavi T, et al. Eosinophilic cystitis in a 4-year-old boy: successful long-term treatment with cyclosporin A. Pediatrics. 2001;108(6):E113. doi: https://doi.org/10.1542/peds.108.6.e113
Yamada T, Taguchi H. [Clinical study of interstitial cystitis. I-(I). The clinical and pathological observations of the contracted bladder caused by interstitial cystitis and tuberculosis]. Nihon Hinyokika Gakkai Zasshi. 1984;75(4):638–45.
Thompson RH, Dicks D, Kramer SA. Clinical manifestations and functional outcomes in children with eosinophilic cystitis. Journal of Urology. 2005;174(6):2347–9. doi: https://doi.org/10.1097/01.ju.0000180423.06285.72
Schmitz-Dräger BJ, Skutetzki A, Rieker RJ, Schwab SA, Stöhr R, Bismarck E, et al. Eosinophilic cystitis mimicking bladder cancer—considerations on the management based upon a case report and a review of the literature. Virchows Arch. 2021;479(3):523–7. doi: https://doi.org/10.1007/s00428-021-03049-x
Zhou AG, Amin A, Yates JK, Diamond DA, Tyminski MM, Badway JA, et al. Mass Forming Eosinophilic Cystitis in Pediatric Patients. Urology. 2017;101:139–41. doi: https://doi.org/10.1016/j.urology.2016.11.002
He J, Ning F, Tu L, Hu J, Chen W, Zhao Y. Eosinophilic cystitis in children: A case report. Exp Ther Med. 2018;16(4). https://doi.org/10.3892/etm.2018.6578
Zaman SR, Vermeulen TL, Parry J. Eosinophilic cystitis: treatment with intravesical steroids and oral antihistamines. Case Reports. 2013;2013:bcr2013009327. doi: http://dx.doi.org/10.1136/bcr-2013-009327
Luo Y-B, Gao Q, Guo J, Zhang Y, Sun J, Li W-Y, et al. Ultrasound-guided co-axial introducer needle biopsy in the diagnosis of eosinophilic cystitis in children. Chinese Medical Journal. 2021;134(15):1872–3. doi: https://doi.org/10.1097/cm9.0000000000001564
Runge SB, Høyer S, Winding L. Macroscopic Hematuria and a Bladder Mass: Eosinophilic Cystitis in a 7-Year-Old Boy. Case Reports in Radiology. 2016;2016:1–4. doi: https://doi.org/10.1155/2016/9346218
Sparks S, Kaplan A, DeCambre M, Kaplan G, Holmes N. Eosinophilic cystitis in the pediatric population: A case series and review of the literature. Journal of Pediatric Urology. 2013;9(6):738–44. doi: https://doi.org/10.1016/j.jpurol.2012.11.004
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