Urinary tract infection etiology and antimicrobial sensitivity in a Mexican hospital from 2010 to 2015


  • José L. Villalobos Ayala




BACKGROUND: urinary tract infections are common in both community-based and hospitalized patients. The complexity of their management is increasing, as a result of antimicrobial resistance.

OBJECTIVE: to assess the prevalence and antimicrobial susceptibility profile of uropathogens present in urine cultures analyzed at the Hospital Regional ISSSTE, Monterrey, Nuevo Léon, Mexico.

MATERIALS AND METHODS: a retrospective cohort study was conducted, based on urine sample analyses performed at the hospital laboratory between January 2010 and September 2015.

RESULTS: data on 4,394 urine cultures were obtained. Escherichia coli was identified in 47.1% of the isolates. A total of 59.4% of the Escherichia coli and 59.6% of the Klebsiella pneumoniae isolates showed production of extended-spectrum beta-lactamases. Candida albicans was found in 3.6% of the isolates. Most of the Escherichia coli and Klebsiella pneumoniae isolates showed sensitivity to carbapenems.

CONCLUSIONS: these study results provide valuable insight for improving urinary tract infection management at the Hospital Regional ISSSTE of Monterrey. Institutions elsewhere should carry out these investigations, to understand antimicrobial resistance trends in their area of activity and improve their antimicrobial prescription practices. 

KEY WORDS: urinary tract infection, UTI, uropathogens, antimicrobial sensitivity






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